The mean goal of this training program is to provide opportunities to students in the practical work in the field of engineering

The mean goal of this training program is to provide opportunities to students in the practical work in the field of engineering, environmental and safety to enhance the professional skills and interpersonal skills as a professional.

Hikma Pharmaceuticals is an international pharmaceutical company based in Jordan, that manufactures non-branded generic and in-licensed pharmaceutical products.

The vision is of a healthier world that enriches all of our communities. The vision is of a healthier world that enriches all of our communities. Throughout last 40 years, the company has been guided by the simple belief that when world-class medicine is put within people’s reach, it has the ability to transform their lives and their communities. Today at Hikma they now have the reach, insight and expertise to transform so many more people’s lives.

And their mission creates high quality medicines, and they make them accessible and affordable to the people who need them, and they put better health within reach, every day.

The projects that being given to me are understand SOP of machine that used to make medicine, verify the quality of product through testing analysis and learning from operator controlling process.

Objectives of the project
To deliver high-quality, affordable generic and branded generic medicines to patients.

To lay down standard operating procedures of machines.

To get more experience on controlling process of machine and verifying the quality of product.
1.2.2 Scope of projects
Based on the objectives, the scope of the study of this work are:
Ensure effective organizations, leadership and management.
Know the work flow of manufacture tablets, ointment and liquid.

Develop more complex and differentiated products and use innovative technologies.

During my training I was distributed in different units starting from powdering area then to compression, coating, blistering, ointment and ending in liquid.

Powdering areaThe raw material is sent to weighing area by warehouse and before that the room must be cleaned carefully to make sure there is no suspend material left there, after that it move to powder blinding and granulation.

Powder blinding
My work there were to write code NO. of each bag in Batch Manufacture Record (BMR), check the weight of bags before they move to blinder and learning standard operating procedure for V-blinder machine:
The process of powder blinding about solid dose and powder contain multiple ingredients, these include an Active Pharmaceutical Ingredient (API) and numerous excipients which include fillers, binders to name a few
2.1.2 Granulation
After blending powder the material then move to granulation process, in the pharmaceutical industry, granulation refers to the act or process in which primary powder particles are made to form larger, multiparticle entities called granules. Granulation it’s the process of collecting particles together by creating bonds between them. Bonds are formed by compression
2.2 Tablet Compression
After the preparation of granules they are compressed to get final product. There are two machines are used Sejong MRC for tablets and capsuling machine. And my job here was to testify the hardness and weight of tablets by using analyzes testing machine.

The compression is done by single punch machine The tablet press is a high-speed mechanical device. It compresses the ingredients into the required tablet shape with extreme accurate. It can make the tablet in many shapes, although they are usually round or oval. Also,
When the powder being compression as tablets then the coating process it’s applies an eaten paint on the surface of a pharmaceutical dosage form to achieve specific benefits. This is an additional process in tableting which causes an increase in the cost of tablet production.

During this process I was recording temperature of solution that will cover tablets which should be between 55 ?C to 70 ?C and trying final product on HCL solution to verify whether can be dissolve in stomach or not.

2.3.1 Objectives of coating:To mask the unpleasant odor, color or taste of the tablet.

To offer a physical or chemical protection to the drug.

To help maintain the shape of tablets.

To wear resistance and make thermal insulation
Now after coating tablets the last process is blistering  commonly used as unit-dose packaging for pharmaceutical tablets or capsules. Blister packs can provide barrier protection for shelf life requirements,
2.4.2 Objective of blisterCost savings. Advertising space. There is a wide range of colors and finishes that blister packaging can be constructed to feature. Clear product display. Theft deterrent packaging. To prevent retail theft, packages are specifically designed so that the customer cannot “touch and feel” the productQuality Assurance and Quality ControlIn last week after I pass through all manufacturing in plant, my work was to QA and QC worker to understand the concept on management plan. I was following the Industrial Revolution and the rise of mass production, it became important to better define and control the quality of products. Originally, the goal of quality was to ensure that engineering requirements were met in final products. Later, as manufacturing processes became more complex, quality developed into a discipline for controlling process variation as a means of producing quality products. Also, my work was involved for verification of output conformance to desired quality levels. This means that the ICT solution is checked against customer requirements, with various checks being conducted at planned points in the development lifecycle.